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Summary

Description
English: A current model of meiotic recombination, initiated by a double-strand break or gap, followed by pairing with an homologous chromosome and strand invasion to initiate the recombinational repair process. Repair of the gap can lead to crossover (CO) or non-crossover (NCO) of the flanking regions. CO recombination is thought to occur by the Double Holliday Junction (DHJ) model, illustrated on the right, above. NCO recombinants are thought to occur primarily by the Synthesis Dependent Strand Annealing (SDSA) model, illustrated on the left, above. Most recombination events appear to be the SDSA type.
Date
Source Meiosis as an Evolutionary Adaptation for DNA Repair. Chapter 19 in DNA Repair. Inna Kruman editor. InTech Open Publisher. DOI: 10.5772/25117 http://www.intechopen.com/books/dna-repair/meiosis-as-an-evolutionary-adaptation-for-dna-repair
Author Harris Bernstein, Carol Bernstein and Richard E. Michod

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inception

27 July 2013

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Date/TimeThumbnailDimensionsUserComment
current16:14, 23 October 2013Thumbnail for version as of 16:14, 23 October 2013393 × 470 (24 KB)Bernstein0275This is a more accurate version of SDSA. This version also eliminates one unnecessary step in both recombinational repair pathways.
23:51, 27 July 2013Thumbnail for version as of 23:51, 27 July 20131,630 × 2,292 (155 KB)Bernstein0275User created page with UploadWizard

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