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Peyote
Peyote in the wild
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Order: Caryophyllales
Family: Cactaceae
Subfamily: Cactoideae
Genus: Lophophora
Species:
L. williamsii
Binomial name
Lophophora williamsii
(Lem. ex J.F.Cels) J.M.Coult.
Synonyms

Echinocactus williamsii Lemaire ex Salm-Dyck
Lophophora lewinii (K. Schumann) Rusby
Lophophora echinata Croizat
Lophophora fricii Habermann
L. williamsii var. fricii (Habermann) Grym
L. diffusa subsp. fricii (Habermann) Halda
Lophophora jourdaniana Haberman

The peyote (/pˈti/; Lophophora williamsii /ləˈfɒfərə wɪliˈæmzi/) is a small, spineless cactus which contains psychoactive alkaloids,[2] particularly mescaline (see also: cactus alkaloids).[3] Peyote is a Spanish word derived from the Nahuatl peyōtl ([ˈpejoːt͡ɬ]), meaning "caterpillar cocoon", from a root peyōni, "to glisten".[4][5][6] Peyote is native to Mexico and southwestern Texas. It is found primarily in the Sierra Madre Occidental, the Chihuahuan Desert and in the states of Nayarit, Coahuila, Nuevo León, Tamaulipas, and San Luis Potosí among scrub. It flowers from March to May, and sometimes as late as September. The flowers are pink, with thigmotactic anthers (like Opuntia).

Known for its psychoactive properties when ingested, peyote has at least 5,500 years of entheogenic and medicinal use by indigenous North Americans.[7]

Description

A group of Lophophora williamsii
A flowering peyote

The various species of the genus Lophophora grow low to the ground and they often form groups with numerous, crowded shoots. The blue-green, yellow-green or sometimes reddish-green shoots are mostly flattened spheres with sunken shoot tips. They can reach heights of 2 to 7 centimeters (0.79 to 2.76 in) and diameters of 4 to 12 cm (1.6 to 4.7 in). There are often significant, vertical ribs consisting of low and rounded or hump-like bumps. From the cusp areoles arises a tuft of soft, yellowish or whitish woolly hairs. Spines are absent. Flowers are pink or white to slightly yellowish, sometimes reddish. They open during the day, are from 1 to 2.4 cm (0.39 to 0.94 in) long, and reach a diameter from 1 to 2.2 cm (0.39 to 0.87 in).

Lophophora williamsii seedling at roughly 1+12 months of age

The cactus produces flowers sporadically; these are followed by small edible pink fruit. The club-shaped to elongated, fleshy fruits are bare and more or less rosy colored. At maturity, they are brownish-white and dry. The fruits do not burst open on their own and they are between 1.5 to 2 cm (0.59 to 0.79 in) long. They contain black, pear-shaped seeds that are 1 to 1.5 mm long and 1 mm wide. The seeds require hot and humid conditions to germinate. Peyote contains a large spectrum of phenethylamine alkaloids.[2] The principal one is mescaline for which the content of Lophophora williamsii is about 0.4% fresh (undried) and 3–6% dried.[8]

Taxonomy

French botanist Charles Antoine Lemaire described the species as Echinocactus williamsii in 1845. It was placed in the new genus Lophophora in 1894 by American botanist John Merle Coulter.

Distribution and habitat

Range of wild peyote

L. williamsii is native to southern North America, mainly distributed in Mexico. In the United States, it grows in Southern Texas. In Mexico, it grows in the states of Chihuahua, Coahuila, Nuevo León, and Tamaulipas in the north to San Luis Potosi and Zacatecas.[9][10][11] It is primarily found at elevations of 100 to 1,500 m (330 to 4,920 ft) and exceptionally up to 1,900 m (6,200 ft) in the Chihuahuan desert, but is also present in the milder climate of Tamaulipas. Its habitat is primarily in desert scrub, particularly thorn scrub in Tamaulipas. It is common on or near limestone hills.[12]

Cultivation

Peyote is extremely slow growing. Cultivated specimens grow considerably faster, sometimes taking less than three years to go from seedling to mature flowering adult. More rapid growth can be achieved by grafting peyote onto mature San Pedro root stock. The top of the above-ground part of the cactus, the crown, consists of disc-shaped buttons. These are cut above the roots and sometimes dried. When done properly, the top of the root forms a callus and the root does not rot. When poor harvesting techniques are used, however, the entire plant dies.[13] Currently in South Texas, peyote grows naturally but has been over-harvested, to the point that the state has listed it as an endangered species.[14] Cultivation is an important conservation tool for this particular species.[15] Promoting San Pedro as a Peyote substitute may act as an intervention to reduce Peyote consumption.[16]

Uses

Psychoactivity and folk medicine

Dried Peyote (Lophophora williamsii), containing around 5-6% mescaline by weight

When used for its psychoactive properties, common doses for pure mescaline range from roughly 200 to 400 mg. This translates to a dose of roughly 10 to 20 g of dried peyote buttons of average potency; however, potency varies considerably between samples, making it difficult to measure doses accurately without first extracting the mescaline. The concentration of mescaline is typically highest at the sides of the peyote button.[17] The effects last about 10 to 12 hours.[18] Peyote is reported to trigger rich visual or auditory effects (see synesthesia) and spiritual or philosophical insights.[19][20]

In addition to psychoactive use, some Native American tribes use the plant in folk medicine. They employ peyote for varied ailments.[21] Although uncommon, use of peyote and mescaline has been associated with poisoning.[22] Peyote contains the alkaloid, hordenine (also called peyocactin).[23]

Chemical structure of hordenine (peyocactin), a compound contained in the peyote cactus

History

In 2005, researchers used radiocarbon dating and alkaloid analysis to study two specimens of peyote buttons found in archaeological digs from a site called Shumla Cave No. 5 on the Rio Grande in Texas. The results dated the specimens to between 3780 and 3660 BCE. Alkaloid extraction yielded approximately 2% of the alkaloids including mescaline in both samples. This indicates that native North Americans were likely to have used peyote since at least 5500 years ago.[24]

Specimens from a burial cave in west central Coahuila, Mexico have been similarly analyzed and dated to 810 to 1070 CE.[25]

Peyote in Wirikuta, Mexico

From earliest recorded time, peyote has been used by indigenous peoples, such as the Huichol[26] of northern Mexico and by various Native American tribes, native to or relocated to the Southern Plains states of present-day Oklahoma and Texas. Its usage was also recorded among various Southwestern Athabaskan-language tribal groups. The Tonkawa, the Mescalero, and Lipan Apache were the source or first practitioners of peyote religion in the regions north of present-day Mexico.[27] They were also the principal group to introduce peyote to newly arrived migrants, such as the Comanche and Kiowa from the Northern Plains. The religious, ceremonial, and healing uses of peyote may date back over 2000 years.[28]

Under the auspices of what came to be known as the Native American Church, in the 19th century, American Indians in more widespread regions to the north began to use peyote in religious practices, as part of a revival of native spirituality. Its members refer to peyote as "the sacred medicine", and use it to combat spiritual, physical, and other social ills. Concerned about the drug's psychoactive effects, between the 1880s and 1930s, U.S. authorities attempted to ban Native American religious rituals involving peyote, including the Ghost Dance. Today the Native American Church is one among several religious organizations to use peyote as part of its religious practice. Some users claim the drug connects them to God.[29]

Traditional Navajo belief or ceremonial practice did not mention the use of peyote before its introduction by the neighboring Utes. The Navajo Nation now has the most members of the Native American Church.[citation needed]

Since 1846, the official Mexican Pharmacopoeia recommended the use of peyote extract in “microdose” as a tonic for the heart.[30]

John Raleigh Briggs (1851–1907) was the first to draw scientific attention of the Western scientific world to peyote.[31] Louis Lewin described Anhalonium lewinii in 1888.[32] British sexologist Havelock Ellis self experimented with it on Good Friday 1896, publishing details in 1898.[33] Arthur Heffter conducted self experiments on its effects in 1897.[34] Similarly, Norwegian ethnographer Carl Sofus Lumholtz[35] studied and wrote about the use of peyote among the Indians of Mexico. Lumholtz also reported that, lacking other intoxicants, Texas Rangers captured by Union forces during the American Civil War soaked peyote buttons in water and became "intoxicated with the liquid".[36]

Adverse reactions

A study published in 2007 found no evidence of long-term cognitive problems related to peyote use in Native American Church ceremonies, but researchers stressed their results may not apply to those who use peyote in other contexts.[37] A four-year large-scale study of Navajo who regularly ingested peyote found only one case where peyote was associated with a psychotic break in an otherwise healthy person; other psychotic episodes were attributed to peyote use in conjunction with pre-existing substance abuse or mental health problems.[38] Later research found that those with pre-existing mental health issues are more likely to have adverse reactions to peyote.[39] Peyote use does not appear to be associated with hallucinogen persisting perception disorder (a.k.a. "flashbacks") after religious use.[40] Peyote also does not seem to be associated with physical dependence, but some users may experience psychological dependence.[41]

Peyote can have strong emetic effects, and one death has been attributed to esophageal bleeding caused by vomiting after peyote ingestion in a Native American patient with a history of alcohol abuse.[42] Peyote is also known to cause potentially serious variations in heart rate, blood pressure, breathing, and pupillary dilation.[43][22]

Research into the Huichol natives of central-western Mexico, who have taken peyote regularly for an estimated 1,500 years or more, found no evidence of chromosome damage in either men or women.[44]

According to a statement made by Gertrude Bonnin in 1916, a member of the Sioux tribe, the use of Peyote had been the direct cause of death among 25 Utes in last two years.[45]

Cultural significance

Wixarika (Huichol) culture

The Wixarika religion consists of four principal deities: Corn, Kayumarie (Blue Deer), Hikuri (Peyote), and the Eagle, all descended from their Sun God. Schaefer has interpreted this to mean that peyote is the soul of their religious culture and a visionary sacrament that opens a pathway to the other deities.[46]

Religion

Native American Church

Peyote is considered sacramental and sacred in the Native American Church, also known as Peyotism. It is used in rituals for "a closer understanding of the spiritual world"[47] and to commune with God and the spirits (including the deceased) in order to receive spiritual power, guidance, reproof, and healing. To many followers, peyote itself is personified as "Peyote Spirit", considered to be either God's equivalent for the Indians to Jesus for mainstream Christians, or Jesus himself.[48]

Peyote is consumed during an all-night healing ceremony inside a hogan, a traditional Navajo building, or a tipi. The ritual starts around 8 P.M Saturday, and includes prayer, singing, sacramental eating of peyote, water rites, and contemplation. It concludes with a communion breakfast on Sunday morning.[48]

Legality

United Nations

Canada

Mescaline is listed as a Schedule III controlled substance under the Canadian Controlled Drugs and Substances Act, but peyote is specifically exempt.[49] Possession and use of peyote plants is legal.[50]

United States

Non-drug uses of peyote in religious ceremonies by the Native American Church and its members is exempt from registration.[51] This law has been codified as a statute in the American Indian Religious Freedom Act of 1978, and made part of the common law in Peyote Way Church of God, Inc. v. Thornburgh, (5th Cir. 1991);[52] it is also in administrative law at the 21 CFR 1307.31 which states for "Special Exempt Persons":

Section 1307.31 Native American Church. The listing of peyote as a controlled substance in Schedule I does not apply to the nondrug use of peyote in bona fide religious ceremonies of the Native American Church, and members of the Native American Church so using peyote are exempt from registration. Any person who manufactures peyote for or distributes peyote to the Native American Church, however, is required to obtain registration annually and to comply with all other requirements of law.

U.S. v. Boyll, 774 F.Supp. 1333 (D.N.M. 1991)[53] addresses this racial issue specifically and concludes:

For the reasons set out in this Memorandum Opinion and Order, the Court holds that, pursuant to 21 C.F.R. § 1307.31 (1990), the classification of peyote as a Schedule I controlled substance, see 21 U.S.C. § 812(c), Schedule I(c)(12), does not apply to the importation, possession or use of peyote for 'bona fide' ceremonial use by members of the Native American Church, regardless of race.

Following the passage of the American Indian Religious Freedom Act Amendments of 1994, United States federal law (and many state laws) protects the harvest, possession, consumption and cultivation of peyote as part of "bona fide religious ceremonies" the federal statute is the American Indian Religious Freedom Act, codified at 42 U.S.C. § 1996a, "Traditional Indian religious use of the peyote sacrament", exempting only use by Native American persons. US v. Boyll expanded permitted use to all persons engaged in traditional Indian religious use, regardless of race. All US states with the exception of Idaho, Utah, and Texas allow usage by non-native, non-enrolled persons in the context of ceremonies of the Native American Church. Some states such as Arizona additionally exempt any general bona fide religious activity or spiritual intent. US jurisdictions enacted these specific statutory exemptions in reaction to the US Supreme Court's decision in Employment Division v. Smith, 494 U.S. 872 (1990), which held that laws prohibiting the use of peyote that do not specifically exempt religious use nevertheless do not violate the Free Exercise Clause of the First Amendment. Though use in Native American Church ceremonies or traditional Indian religious use, regardless of race, is legal under US federal law and additional uses are legal under some state laws, peyote is listed by the United States DEA as a Schedule I controlled substance.[54]

The US military prohibits inductees from enlistment for prior drug usage, however past usage of peyote is permissible if found to be used in accordance with Native American cultural practices.[55]

See also

References

  1. ^ Terry, M. (2017). "Lophophora williamsii". IUCN Red List of Threatened Species. 2017: e.T151962A121515326. doi:10.2305/IUCN.UK.2017-3.RLTS.T151962A121515326.en. Retrieved 19 November 2021.
  2. ^ a b Bauer, Barbara E. (2021-11-01). "The Compounds in Psychedelic Cacti". Psychedelic Science Review. Retrieved 2022-04-01.
  3. ^ Salak, Kira. "Lost Souls of the Peyote Trail (published in National Geographic Adventure)". Kira Salak. Kira Salak, KiraSalak.com. Retrieved 2013-09-12.
  4. ^ Other sources, apparently incorrectly, translate the Nahuatl word as "divine messenger". Anderson, Edward F. (2001). The Cactus Family. Pentland, Oregon: Timber Press. ISBN 978-0-88192-498-5. p. 396.
  5. ^ "Peyote". The American Heritage Dictionary of the English Language. Houghton Mifflin Harcourt Publishing Company. 2020.
  6. ^ Andrews, J. Richard (2003). Workbook for Introduction to Classical Nahuatl, Revised Edition. University of Oklahoma Press. ISBN 978-0-8061-3453-6. p. 246. See peyotl in Wiktionary.
  7. ^ Johnson, Jon (24 June 2020). "What to know about peyote".
  8. ^ "Lophophora". Visionary Cactus Guide. Erowid.org. 2008-03-08. Retrieved 2013-09-12.
  9. ^ Martin, Terry (July 2008). "Stalking the wild Lophophora Part 1: Chihuahua and Coahuila" (PDF). Cactus and Succulent Journal. 80 (4). Cactus and Succulent Society of America: 181–186. doi:10.2985/0007-9367(2008)80[181:STWL]2.0.CO;2. ISSN 0007-9367. S2CID 49320798. Archived from the original (PDF) on 2014-10-06. Retrieved 2013-09-12.
  10. ^ Martin, Terry (September 2008). "Stalking the wild Lophophora Part 2: Zacatecas, San Luis potosí, Nuevo León, and Tamaulipas" (PDF). Cactus and Succulent Journal. 80 (5). Cactus and Succulent Society of America: 222–228. doi:10.2985/0007-9367(2008)80[222:STWL]2.0.CO;2. ISSN 0007-9367. S2CID 90032958. Archived from the original (PDF) on 2014-10-06. Retrieved 2013-09-12.
  11. ^ Martin, Terry (November 2008). "Stalking the wild Lophophora Part 3: San Luis Potosí (central), Querétaro, and Mexico City" (PDF). Cactus and Succulent Journal. 80 (6). Cactus and Succulent Society of America: 310–317. doi:10.2985/0007-9367-80.6.310. ISSN 0007-9367. S2CID 85180357. Archived from the original (PDF) on 2014-10-06. Retrieved 2013-09-12.
  12. ^ Zimmerman, Allan D.; Parfitt, Bruce D. (2006). "Lophophora williamsii". Flora of North America. Vol. 4. Oxford: Oxford University Press. p. 242.
  13. ^ "Harvesting Technique". Cactus Conservation Institute. Retrieved 2022-04-02.
  14. ^ Mchem, Benjamin Bury (2021-08-02). "Could Synthetic Mescaline Protect Declining Peyote Populations?". Chacruna. Retrieved 2022-01-01.
  15. ^ Ermakova, Anna O.; Terry, Martin K.; Trout, Keeper (2022-05-23). "Cultivation as a conservation tool for cacti: review of the botanical evidence and a case study of Lophophora williamsii". Bradleya. 2022 (sp40): 71–82. doi:10.25223/brad.sp40.2022.a8. ISSN 0265-086X. S2CID 248989923.
  16. ^ Engel, L.; Barratt, M.; Ferris, J.; Puljevic, C.; Winstock, A. (2023). "Choosing San Pedro or Peyote". The Mescaline Garden. Retrieved 2023-12-11.
  17. ^ Van Der Sypt, Frederick (2022-04-03). "Validation and exploratory application of a simple, rapid and economical procedure (MESQ) for the quantification of mescaline in fresh cactus tissue and aqueous cactus extracts". PhytoChem & BioSub Journal. doi:10.5281/zenodo.6409376.
  18. ^ Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.
  19. ^ Orsolini, L; Papanti, G. D; De Berardis, D; Guirguis, A; Corkery, J. M; Schifano, F (2017). "The "Endless Trip" among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review". Frontiers in Psychiatry. 8: 240. doi:10.3389/fpsyt.2017.00240. PMC 5701998. PMID 29209235.
  20. ^ Halberstadt, A. L (2014). "Recent Advances in the Neuropsychopharmacology of Serotonergic Hallucinogens". Behavioural Brain Research. 277: 99–120. doi:10.1016/j.bbr.2014.07.016. PMC 4642895. PMID 25036425.
  21. ^ Schultes, Richard Evans (1938). "The appeal of peyote (Lophophora williamsii) as a medicine". American Anthropologist. 40 (4): 698–715. doi:10.1525/aa.1938.40.4.02a00100.
  22. ^ a b Carstairs, S. D; Cantrell, F. L (2010). "Peyote and mescaline exposures: A 12-year review of a statewide poison center database". Clinical Toxicology. 48 (4): 350–3. doi:10.3109/15563650903586745. PMID 20170392. S2CID 39261212.
  23. ^ McCleary, J.A.; Sypherd, P.S.; Walkington, D.L. (1960). "Antibiotic Activity of an Extract Of Peyote [Lophophora williamsii (Lemaire) Coulter]". Economic Botany. 14 (3): 247–249. Bibcode:1960EcBot..14..247M. doi:10.1007/bf02907956. S2CID 41659698.
  24. ^ El-Seedi HR, De Smet PA, Beck O, Possnert G, Bruhn JG (October 2005). "Prehistoric peyote use: alkaloid analysis and radiocarbon dating of archaeological specimens of Lophophora from Texas". J Ethnopharmacol. 101 (1–3): 238–42. doi:10.1016/j.jep.2005.04.022. PMID 15990261.
  25. ^ Bruhn JG, Lindgren JE, Holmstedt B, Adovasio JM (March 1978). "Peyote Alkaloids: Identification in a Prehistoric Specimen of Lophophora from Coahuila, Mexico". Science. 199 (4336): 1437–1438. Bibcode:1978Sci...199.1437B. doi:10.1126/science.199.4336.1437. PMID 17796678. S2CID 19355963.
  26. ^ Lumholtz, Carl, Unknown Mexico, New York: Scribners, 1902
  27. ^ Opler, Morris Edward (2008) [1938]. "The use of Peyote by the Carrizo and Lipan Apache tribes". American Ethnography Quasimonthly. Retrieved 19 January 2009.
  28. ^ Schultes, Richard Evans (2008) [1938]. "The appeal of peyote (Lophophora Williamsii) as a medicine". American Ethnography Quasimonthly. Retrieved 19 January 2009.
  29. ^ "The people who take drugs to see God". BBC News. 21 August 2016.
  30. ^ Olvera-Hernández, Nidia (2023-07-05). "Old Uses of Peyote in Traditional Mexican Medicine and its Inclusion in Official Pharmacopeia". Chacruna. Retrieved 2024-06-22.
  31. ^ {{cite journal %2FBF02862854 | doi=10.1007/BF02862854 | title=Early peyote research an interdisciplinary study | year=1973 | last1=Bruhn | first1=Jan G. | last2=Holmstedt | first2=Bo | journal=Economic Botany | volume=28 | issue=4 | pages=353–390 | s2cid=6988545 }}
  32. ^ Lewin, Louis (1888-05-18). "Ueber Anhalonium Lewinii". Archiv für Experimentelle Pathologie und Pharmakologie (in German). 24 (6): 401–411. doi:10.1007/bf01923627. S2CID 38375777.
  33. ^ "Mescal: A New Artificial Paradise". The Contemporary Review. LXXIII. 1898.
  34. ^ Daniel Perrine, "Visions of the Night: Western Medicine Meets Peyote, 1887–1899" Archived 2008-07-22 at the Wayback Machine, in The Heffter Review of Psychedelic Research, Vol. 2, 2001, p.42, accessed 15 Nov 2009
  35. ^ Lumholtz, Carl, Unknown Mexico, New York: Scribners (1902)
  36. ^ Lumholtz, Carl, Unknown Mexico, New York: Scribners (1902), p.358
  37. ^ Halpern JH, Sherwood AR, Hudson JI, Yurgelun-Todd D, Pope HG Jr. "Psychological and cognitive effects of long-term peyote use among Native Americans." Biol Psychiatry. 2005;58(8):624–631.
  38. ^ Bergman RL (1971). "Navajo peyote use: its apparent safety," Amer J Psychiat 128(6):695–699[51–55].
  39. ^ Inaba, D.S. & Cohen, W.E. (2004). Uppers, Downers, All Arounders. (pp. 229–230, 232). Oregon: CNS Publications, Inc.
  40. ^ Halpern, J. H. (1996). "The use of hallucinogens in the treatment of addiction." Addiction Research, 4(2);177–189.
  41. ^ Hyman, S. E. & Malenka, R. C. (2001). "Addiction and the brain: The neurobiology of compulsion and its persistence." Neuroscience. 2;696
  42. ^ K B Nolte and R E Zumwalt. "Fatal peyote ingestion associated with Mallory-Weiss lacerations." West J Med. 1999 Jun; 170(6): 328.
  43. ^ Nole and Zumwalt 1999 [full citation needed]
  44. ^ Dorrance; Janiger; and Teplitz (1975), "Effect of peyote on human chromosomes: Cytogenic study of the Huichol Indians of northern Mexico." JAMA 234:299–302.
  45. ^ Catches, Vincent (1991). "Native American Church: The Half-Moon Way". Wíčazo Ša Review. 7 (1): 17–24. doi:10.2307/1409324. JSTOR 1409324.
  46. ^ Stacy B. Schaefer, Peter T. Furst. People of the Peyote: Huichol Indian History, Religion, and Survival. UNM Press, 1997. Pg 52–53
  47. ^ Beyer, Catharine (2023-11-11). "Why Can the Native American Church Still Use Peyote?". Learn Religions. Retrieved 2023-11-11.
  48. ^ a b "Native American Church | Peyote Religion, Ceremonies & History | Britannica". www.britannica.com. Retrieved 2023-11-11.
  49. ^ laws-lois.justice.gc.ca, Controlled Drugs and Substances Act – S.C. 1996, c. 19 (SCHEDULE III), accessed 26 Feb 2020
  50. ^ cbc.ca; CBC News: Psychedelic use spreads in B.C. native community, accessed 15 Aug 2016.
  51. ^ "Section 1307.31 Native American Church". Code of Federal Regulations. U.S. Department of Justice Drug Enforcement Administration Office of Diversion Control. Archived from the original on 2015-10-01. Retrieved 2013-09-12.
  52. ^ James W.H. McCord, Sandra McCord, and C. Suzanne Bailey, Criminal and Procedure for the Paralegal: A Systems Approach, p. 178–179 (4th ed. Delmar Cengage 2012) ISBN 978-1-4354-4016-6
  53. ^ UNITED STATES of America, Plaintiff, v. Robert Lawrence BOYLL, Defendant., Crim. No. 90-207-JB, 774 F.Supp. 133 (D.N.M. 1991) (United States District Court, D. New Mexico 1991-09-03).
  54. ^ "Substance: Peyote, DEA#: 7415, CSA SCH: I, NARC: N, Other names: Cactus which contains mescaline" (PDF).
  55. ^ "Navy Recruiting Manual-Enlisted COMNAVCRUITCOMINST 1130.8F" (PDF). Archived from the original (PDF) on 2004-07-12.

Further reading

  • Calabrese, Joseph D. "The Therapeutic Use of Peyote in the Native American Church" Chapter 3 in Vol. 1 of Psychedelic Medicine: New Evidence for Hallucinogens as Treatments, Michael J. Winkelman and Thomas B. Roberts (editors) (2007). Westport, CT: Praeger/Greenwood.
  • Dawson, Alexander S. 2018. The Peyote Effect: From the Inquisition to the War on Drugs. University of California Press, 2018.
  • Jay, Mike. 2019. Mescaline: A Global History of the First Psychedelic. Yale University Press
  • Feeney, Kevin. "The Legal Basis for Religious Peyote Use." Chapter 13 in Vol 1 of Psychedelic Medicine: New Evidence for Hallucinogens as Treatments, Michael J. Winkelman and Thomas B. Roberts (editors) (2007). Westport, CT: Praeger/Greenwood.
  • Baggot, Matthew J. A Note on the Safety of Peyote when Used Religiously. Council on Spiritual Practices, 1996.
  • Labate, Beatriz; Cavnar, Clancy: Peyote: History, Tradition, Politics, and Conservation. Praeger, 2016.
  • Rätsch, Christian, The Encyclopedia of Psychoactive Plants, Enthnopharmacology and Its Applications 1998/2005, Rochester, Vermont, Park Street Press, ISBN 978-0-89281-978-2
  • Pollan, Michael 2021 This Is Your Mind on Plants © 2021 Penguin Books