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Isopropamide
Clinical data
MedlinePlusa694006
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • US: ℞-only and Unscheduled
  • In general: unscheduled
Identifiers
  • 4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.028.470 Edit this at Wikidata
Chemical and physical data
FormulaC23H33N2O+
Molar mass353.530 g·mol−1
3D model (JSmol)
  • O=C(N)C(c1ccccc1)(c2ccccc2)CC[N+](C(C)C)(C(C)C)C
  • InChI=1S/C23H32N2O/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26)/p+1 checkY
  • Key:JTPUMZTWMWIVPA-UHFFFAOYSA-O checkY
 ☒NcheckY (what is this?)  (verify)

Isopropamide (R79) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility.[citation needed] Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.[citation needed]

References

Further reading

  • Seeherman R (October 1957). "Isopropamide iodide: a long-acting anticholinergic". Delaware Medical Journal. 29 (10): 265–9. PMID 13473394.
  • Boss Jr EG, Buchanan GC (November 1957). "Effect of isopropamide iodide on basal gastric secretion in the human". Gastroenterology. 33 (5): 730–6. doi:10.1016/S0016-5085(19)35625-2. PMID 13480414.