Knowledge Base Wiki

Search for LIMS content across all our Wiki Knowledge Bases.

Type a search term to find related articles by LIMS subject matter experts gathered from the most trusted and dynamic collaboration tools in the laboratory informatics industry.

乳狀體Mammillary body)是下丘腦中被灰色物質覆蓋着的一對白色乳突,跟其他大腦結構組成邊緣系統。 它們由兩組核組成,即內側乳核和外側乳核[1]神經解剖學通常將乳狀體歸入下丘腦[2]。乳頭體及通過乳腺丘腦道的前丘腦投影,對於情節記憶很重要。根據對具有乳狀體病變的大鼠的觀察報告,內側乳核的損傷會導致空間記憶不足[3]

臨床意義

Wernicke-Korsakoff綜合徵英语Wernicke–Korsakoff syndrome的發病機理暗示了由於缺乏硫胺而引起的對乳狀體損害,症狀包括順向失憶症引起的記憶力減退,表明乳狀體可能對記憶力很重要。 丘腦內側和前核的病變和乳狀體的病變,通常與人類的失憶症有關[4]。乳狀體萎縮還存在於其他幾種疾病中,例如第三腦室的膠樣囊腫英语Colloid cyst阿茲海默症精神分裂症、心力衰竭和睡眠窒息症。 儘管如此,乳狀體的確切功能仍然不清楚[3]

另请参阅

乳头上核

乳头被盖束

參考資料

  1. ^ Vann, SD; Aggleton, JP. The mammillary bodies: two memory systems in one?. Nature reviews. Neuroscience. 2004-01, 5 (1): 35–44 [2020-01-15]. PMID 14708002. doi:10.1038/nrn1299. (原始内容存档于2020-01-15). 页面存档备份,存于互联网档案馆
  2. ^ Wells, Joseph. Human neuroanatomy, 8th edition. Edited by W. B. Carpenter, J. Sutin, 872 pp, Williams & Wilkins, Baltimore, MD, 1983. $44.00. Muscle & Nerve. 1983-07, 6 (6): 462–462. doi:10.1002/mus.880060612. 
  3. ^ 3.0 3.1 Vann, SD. Re-evaluating the role of the mammillary bodies in memory.. Neuropsychologia. 2010-07, 48 (8): 2316–27 [2020-01-15]. PMID 19879886. doi:10.1016/j.neuropsychologia.2009.10.019. (原始内容存档于2020-01-15). 页面存档备份,存于互联网档案馆
  4. ^ Duprez, TP; Serieh, BA; Raftopoulos, C. Absence of memory dysfunction after bilateral mammillary body and mammillothalamic tract electrode implantation: preliminary experience in three patients.. AJNR. American journal of neuroradiology. 2005-01, 26 (1): 195–7; author reply 197–8 [2020-01-15]. PMID 15661728. (原始内容存档于2020-01-15). 页面存档备份,存于互联网档案馆

外部連結