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Ebalzotan
IUPAC ime
(3R)-N-(propan-2-il)-3-[propan-2-il(propil)amino]-3,4-dihidro-2H-hromen-5-karboksamid
Klinički podaci
Način primeneOralno
Pravni status
Pravni status
  • Uncontrolled
Identifikatori
CAS broj149494-37-1 ДаY
ATC kodnone
PubChemCID 9797080
ChemSpider7972846
UNIIWV4B56N49H ДаY
Hemijski podaci
FormulaC19H30N2O2
Molarna masa318,45 g/mol
  • O=C(NC(C)C)c2cccc1OC[C@H](N(C(C)C)CCC)Cc12

Ebalzotan (NAE-086) je selektivni agonist 5-HT1A receptor.[1][2] On je bio u razvoju kao antidepresiv i anksiolitik, ali je proizvodio nepoželjne nuspojave u fazi I kliničkih ispitivanja te je njegov razvoj prekinut.[1][2]

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Spoljašnje veze

Reference

  1. ^ а б Braish, Tamim; Gadamasetti, Kumar G. (2008). Process chemistry in the pharmaceutical industry, volume 2 challenges in an ever changing climate. Boca Raton: CRC Press. ISBN 978-0-8493-9051-7. 
  2. ^ а б Weaver, Donald F.; Nogrady, Thomas; Nogrady, Th (2005). Medicinal chemistry a molecular and biochemical approach. Oxford [Oxfordshire]: Oxford University Press. ISBN 978-0-19-510455-4. 

Literatura