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Li Despotatu de Serbia (Serbian: Српска деспотовина / Srpska despotovina) esset un state medieval serbian in li unesim medie del 15esim secul. Etsi li Batallie de Kosovo in 1389 es erronimen considerat quam li fine de Serbia medieval, li Despotatu, un successori del Imperie Serbian e Moravian Serbia, durat altri sesant annus, experimentante un renascentie cultural, economic, e politic, specialmen durant li reyie del despot Stefan Lazarević. Pos li morte del despot Đurađ Branković in 1456, li Despotatu continuat a exister por altri tri annus ante que it finalmen cadet sub li ottomanes in 1459.
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