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Atrium may refer to:

• Atrium (heart), an anatomical structure of the heart
• Atrium, the genital structure next to the genital aperture in the reproductive system of gastropods
• Atrium of the ventricular system of the brain
• Pulmonary alveolus (also known as atrium alveolus), microscopic air sac in the lungs

• Atrium (architecture), an open space within a building, either open to the sky or featuring a glass roof
  • Ancient Roman atrium, a grand entrance hall, reception room, and living room in a traditional Roman house.

• Amot Atrium Tower, a tower in Ramat Gan, Israel
• Atrium, Cardiff, a University of South Wales building in Cardiff
• Atrium Building, a skyscraper in Guatemala City
• Atrium Casino, a casino in Dax, France
• Atrium Cinemas, a movie theatre in Karachi, Pakistan
• Winter Garden Atrium, a Brookfield Properties building in the World Financial Center of the World Trade Center, New York City
• Atrium on Bay, a retail and office complex in Toronto, Canada

• Atrium Health, based in Charlotte, North Carolina

• The Atrium (disambiguation)