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CDKL2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCDKL2, KKIAMRE, P56, cyclin dependent kinase like 2
External IDsOMIM: 603442; MGI: 1858227; HomoloGene: 55793; GeneCards: CDKL2; OMA:CDKL2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003948
NM_001330724

NM_001276315
NM_016912
NM_177270

RefSeq (protein)

NP_001317653
NP_003939

NP_001263244
NP_058608
NP_796244

Location (UCSC)Chr 4: 75.58 – 75.63 MbChr 5: 92.01 – 92.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cyclin-dependent kinase-like 2 is an enzyme that in humans is encoded by the CDKL2 gene.[5][6]

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138769Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029403Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Taglienti CA, Wysk M, Davis RJ (Feb 1997). "Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE". Oncogene. 13 (12): 2563–74. PMID 9000130.
  6. ^ a b "Entrez Gene: CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)".

Further reading