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Singles
2021 ABN AMRO World Tennis Tournament
Final
Champion	Andrey Rublev
Runner-up	Márton Fucsovics
Score	7–6(7–4), 6–4
Details
Draw	32 (4 Q / 4 WC )
Seeds	8
Events
Singles Doubles
← 2020 · ABN AMRO World Tennis Tournament · 2022 →

Andrey Rublev defeated Márton Fucsovics in the final, 7–6^(7–4), 6–4 to capture the men's singles tennis title at the 2021 Rotterdam Open. It was Rublev's fourth consecutive ATP Tour 500 victory, dating back to the 2020 Hamburg Open.

Gaël Monfils was the two-time defending champion, but chose not to defend his title.^[1]

Daniil Medvedev was in contention to become the first player outside of the Big Four to reach the world No. 2 ranking since July 24, 2005 if he reached the final.^[2] However, he lost in the first round to Dušan Lajović.

	Semifinals							Final
		Borna Ćorić	4	1
	Q	Márton Fucsovics	6	6
								Q	Márton Fucsovics	64	4
								4	Andrey Rublev	77	6
	4	Andrey Rublev	6	77
	2	Stefanos Tsitsipas	3	62

	First round							Second round							Quarterfinals							Semifinals
	1	D Medvedev	64	4
		D Lajović	77	6					D Lajović	3	2
		B Ćorić	6	77					B Ćorić	6	6
	WC	B van de Zandschulp	4	64												B Ćorić	77	77
		A de Minaur	6	6												K Nishikori	62	64
		J Millman	1	4					A de Minaur	3	6	5
		K Nishikori	77	6					K Nishikori	6	2	7
	7	F Auger-Aliassime	64	1																			B Ćorić	4	1
	3/WC	A Zverev	5	3																		Q	M Fucsovics	6	6
		A Bublik	7	6					A Bublik	77	3	1
		T Paul	6	79					T Paul	65	6	6
		L Sonego	4	67												T Paul	4	3
	Q	M Fucsovics	77	64	77										Q	M Fucsovics	6	6
		R Opelka	62	77	64			Q	M Fucsovics	6	6
		A Davidovich Fokina	6	77					A Davidovich Fokina	3	2
	5	R Bautista Agut	2	63

	First round							Second round							Quarterfinals							Semifinals
	6	D Goffin	6	6
		J-L Struff	4	0				6	D Goffin	63	65
	Q	J Chardy	4	77	77			Q	J Chardy	77	77
		U Humbert	6	65	64										Q	J Chardy	62	77	4
	WC	R Haase	6	62	3										4	A Rublev	77	62	6
	WC	A Murray	2	77	6			WC	A Murray	5	2
	Q	M Giron	61	3				4	A Rublev	7	6
	4	A Rublev	77	6																		4	A Rublev	6	77
	8	S Wawrinka	4	5																		2	S Tsitsipas	3	62
		K Khachanov	6	7					K Khachanov	6	6
		N Basilashvili	0	3				Q	C Norrie	2	2
	Q	C Norrie	6	6												K Khachanov	6	3	5
		H Hurkacz	6	78											2	S Tsitsipas	4	6	7
		A Mannarino	3	66					H Hurkacz	4	6	5
	SE	E Gerasimov	64	5				2	S Tsitsipas	6	4	7
	2	S Tsitsipas	77	7

	First round							Qualifying competition
	1	Márton Fucsovics	6	6
		Arthur Rinderknech	2	4
								1	Márton Fucsovics	6	6
								5	Pierre-Hugues Herbert	4	3
		Václav Šafránek	64	2
	5	Pierre-Hugues Herbert	77	6

	First round							Qualifying competition
	2	Jérémy Chardy	6	4	6
		Tallon Griekspoor	4	6	0
								2	Jérémy Chardy	6	5	6
								8	Antoine Hoang	4	7	4
	WC	Ryan Nijboer	4	0
	8	Antoine Hoang	6	6

	First round							Qualifying competition
	3	Cameron Norrie	6	6
	Alt	Miliaan Niesten	2	0
								3	Cameron Norrie	6	6
								7	Andreas Seppi	3	2
		Maxime Cressy	4	1
	7	Andreas Seppi	6	6

	First round							Qualifying competition
	4	Marcos Giron	6	5	6
	WC	Tim van Rijthoven	2	7	4
								4	Marcos Giron	6	6
								6	Norbert Gombos	3	4
	WC	Jelle Sels	3	62
	6	Norbert Gombos	6	77

• Main draw
• Qualifying draw