Effects of the storage conditions on the stability of natural and synthetic cannabis in biological matrices for forensic toxicology analysis: An update from the literature

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Welcome to the WikiProject Molecular Biology talk page. Please post any comments, suggestions or questions. Also feel free to introduce yourself if you plan on becoming an active editor!

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WikiProject Molecular Biology Archives: 1, 2, 3

Taskforce archives:

MCB: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
Genetics: 1, 2, 3, 4
Computational Biology: 1, 2
Gene Wiki: 1, 2, 3, 4

Biophysics (inactive): 1, 2
Metabolic Pathways (inactive): 1
Cell Signaling (inactive): 1
RNA (inactive): 1

There is a requested move discussion at Talk:3α-Hydroxysteroid dehydrogenase#Requested_move_9_April_2024 that may be of interest to members of this WikiProject. Natg 19 (talk) 23:23, 18 April 2024 (UTC)[reply]

See Talk:AKR1C4#Requested move 9 April 2024 for closed discussion with outcome of 'Move'. --User:Ceyockey (talk to me) 03:38, 16 July 2024 (UTC)[reply]

MID gene

Just a quick question is there any articles about a gene in particular? I’m talking about a gene called MID (minus dominance). There does seem to be a lot of sources about this gene from:

here

here

here

Just asking to make sure it doesn’t go by a different name or something. I’m also wondering if genes here on Wikipedia have a certain style or policies.

Also I am bringing this up to see what y’all think about there being an article on this gene. When researching the evolution of sexes and mating types I noticed a lot of sources keep mentioning this gene.CycoMa1 (talk) 04:52, 2 May 2024 (UTC)[reply]

Wikipedia is a popular encyclopedia intended for a diverse audience. There are 25,000 genes in the human genome and something close to one million different different genes in the biosphere. We do not need to have a separate Wikipedia article for each gene.
But there's another problem that just as important. Any article on an individual genes is certainly going to bring up the definition of a gene and important issues such as regulation, evolution, and alternative splicing. It is proving to be very difficult to get individual editors to stick to the definitions and descriptions of these features that have been thrashed out in the articles specific to those topics. This leads to a lot of confusion and conflict so we should be very cautious about creating any new molecular biology articles unless they are absolutely necessary. Genome42 (talk) 14:57, 2 May 2024 (UTC)[reply]
Does your response suggest that the "Gene Wiki Project" has been abandoned? --User:Ceyockey (talk to me) 03:43, 16 July 2024 (UTC)[reply]

Mitochondrial fatty acid synthesis in lipid-related articles

Hello.

Mitochondrial fatty acid synthesis (mtFASII) is not yet well incorporated into the lipid-related articles or is completely missing in some of them. Therefore I ask for your help.

Could someone revise the introductory section of fatty acid synthesis? It should be clearer and earlier in the text that there are 2 different fatty acid syntheses in humans, cytosolic fatty acid synthesis (FASI) and mitochondrial fatty acid synthesis (mtFASII). The other sections of the article are also not quite coherent, you can simply see that the article was written with the knowledge that fatty acid synthesis only takes place in the cytosol.

In the articles on fatty acid and lipid metabolism, mitochondrial fatty acid synthesis is completely missing. Abvdj (talk) 12:45, 19 May 2024 (UTC)[reply]

Regarding fatty acyl-CoA esters

Hey there! I've been working on adding sources to the article fatty acyl-CoA esters, but since I haven't much expertise in the subject area, I'd like to get some clarification -- in particular, what's the relation between these esters and acyl-CoA itself? It seems the same process of beta-synthesis in mitochondrial metabolism is described in each. Thanks! DeemDeem52 (talk) 16:09, 28 May 2024 (UTC)[reply]

My impression is that they are the same thing, with Fatty acyl-CoA esters having a much more confusing name. Jo-Jo Eumerus (talk) 07:09, 29 May 2024 (UTC)[reply]
Hmm... if that's the case, then perhaps the page should be merged. I'll put in a merge proposal and see if it can't get consensus. Thanks! DeemDeem52 (talk) 14:53, 29 May 2024 (UTC)[reply]

There is a requested move discussion at Talk:Ketone bodies#Requested move 25 May 2024 that may be of interest to members of this WikiProject. Safari ScribeEdits! Talk! 00:15, 2 June 2024 (UTC)[reply]

The outcome of this request was "Not moved". --User:Ceyockey (talk to me) 03:45, 16 July 2024 (UTC)[reply]

Source evaluation requested at Promoter (genetics)

Over at WikiProject Mathematics, we ran into a citation-spamming issue, where references to a substandard book were inserted by a COI editor. The statements being spammed with these citations were, variously, summaries that didn't need to be cluttered with footnotes, already supported by other references, or not actually supported by the spam reference. The article Promoter (genetics) may also have been affected. It would greatly help if a subject-matter specialist could evaluate the two sources (cited a total of seven times between them) co-authored by P. Gagniuc. Are the claims accurate and worth the words spent on them? Should the statements in question be cited to textbooks instead? XOR'easter (talk) 23:14, 14 June 2024 (UTC)[reply]

Looking for some opinions

Please see Wikipedia:External links/Noticeboard#Human mitochondrial genetics. We are looking for opinions about whether some ==External links== would be valuable. WhatamIdoing (talk) 03:32, 19 June 2024 (UTC)[reply]

Hi everybody. I have been hired by UK Biobank to improve the article. I have uploaded an edit request on the talk page which I think would benefit from some specialist knowledge as some of the updates relate to concepts within the scope of this project and COMPBIO. Any help or feedback would be appreciated! Burchrusks (talk) 10:50, 19 June 2024 (UTC)[reply]

ETS2

I've added a bit to the ETS2 article to reflect the latest paper in Nature linking ETS2 with a wide range of inflammatory diseases. Please amend, or even remove, this if what I've written is wrong. — The Anome (talk) 20:59, 22 June 2024 (UTC)[reply]

ETS2 is a fairly important transcription factor, and these often have multiple functions. I think this addition is WP:UNDUE as it emphasizes one function among many, but mostly b/c the article currently doesn't list any other function so I am not sure if it should be removed. Typical problem with well-studied proteins, really. Jo-Jo Eumerus (talk) 17:27, 23 June 2024 (UTC)[reply]
Do we really need to have separate Wikipedia articles for every human gene? I don't think so.
Is it a good idea to insert all the latest speculations about the function of a given gene before they are confirmed by additional experiments in other labs? I don't think so. Genome42 (talk) 19:54, 23 June 2024 (UTC)[reply]

RetractionBot

I posted this story from the Signpost last month. Things have evolved a bit and now Retraction bot handles {{Erratum}}, {{Expression of concern}}, and {{Retracted}}. These populate the following categories:

Extended content
  1. Adrenaline
  2. He Jiankui affair
  3. Akt/PKB signaling pathway
  4. AKT2
  5. Albumin transport function analysis by EPR spectroscopy
  6. Alveolar macrophage
  7. ANGPTL8
  8. Antiglucocorticoid
  9. Apoptosis
  10. Antonio Arnaiz-Villena
  11. Arsenic biochemistry
  12. ABC transporter
  13. Autoimmune disease
  14. Axon guidance
  15. BCAS3
  16. Biotechnology
  17. C9orf3
  18. Calcium signaling in cell division
  19. Cardiac muscle
  20. Cathelicidin antimicrobial peptide
  21. CEBPB
  22. Chorionic villus sampling
  23. CHUK
  24. Class A basic helix-loop-helix protein 15
  25. Collagen, type IV, alpha 1
  26. Cyclin-dependent kinase 2
  27. De novo gene birth
  28. Netrin receptor DCC
  29. DNA ligase 3
  30. DSCAM
  31. Early prostate cancer antigen-2
  32. Garth Ehrlich
  33. EP300
  34. Epigenetics
  35. FAM162A
  36. Florigen
  37. Free fatty acid receptor 4
  38. Galectin-9
  39. Gasotransmitter
  40. Gene-for-gene relationship
  41. Genetically modified organism
  42. GPR132
  43. H+, Na+-translocating pyrophosphatase family
  44. HEPN1
  45. HHV Latency Associated Transcript
  46. HYAL1
  47. Hypoxia-inducible factor
  48. IFI16
  49. Inorganic pyrophosphatase
  50. Large tumor antigen
  51. Let-7 microRNA precursor
  52. List of phylogenetics software
  53. Long non-coding RNA
  54. LOXL2
  55. Lymphocyte expansion molecule
  56. MED12
  57. MED24
  58. Mesenchymal stem cell
  59. MicroRNA
  60. Migration-inducting gene 7
  61. Mir-31
  62. Mir-133 microRNA precursor family
  63. Mir-192/215 microRNA precursor
  64. MiR-203
  65. Mir-802 microRNA precursor family
  66. Msh homeobox 2
  67. MTDH
  68. Neurogenins
  69. Non-coding RNA
  70. Non-mevalonate pathway
  71. Nuclear receptor coactivator 1
  72. Nuclear receptor coactivator 2
  73. Nuclear receptor coactivator 3
  74. Nuclear receptor coregulators
  75. Paracrine signaling
  76. Pericyte
  77. PHLPP
  78. Poly(3-hydroxybutyrate) depolymerase
  79. Prostaglandin EP1 receptor
  80. Protein inhibitor of activated STAT
  81. RAP1B
  82. Regeneration in humans
  83. Reprimo
  84. Ribonuclease L
  85. RNA interference
  86. ROCK1
  87. Séralini affair
  88. SKP2
  89. Slit-Robo
  90. SMARCC2
  91. Somatostatin receptor 2
  92. Sphingosine kinase 1
  93. SRA1
  94. Stem cell
  95. Steroidogenic acute regulatory protein
  96. STK3
  97. Subtelomere
  98. SUCNR1
  99. SUPT16H
  100. TIMD4
  101. TP53-inducible glycolysis and apoptosis regulator
  102. Transformation/transcription domain-associated protein
  103. TSC2
  104. TSG101
  105. Unconventional myosin-Va

If the citation is no longer reliable, then the article needs to be updated, which could be as minor as the removal/replacement of the citation with a reliable one, to rewriting an entire section that was based on flawed premises. If the citation to a retracted paper was intentional, like in the context of a controversy noting that a paper was later retracted, you can replace {{retraction|...}} with {{retraction|...|intentional=yes}}/{{expression of concern|...}} with {{expression of concern|...|intentional=yes}}/{{Erratum|...}} with {{Erratum|...|checked=yes}}.

I put the list of articles within the scope of WP:MCB in collapsed sections. Any help you can give with those are greatly appreciated. Feel free to remove/strike through those you've dealt with. Headbomb {t · c · p · b} 20:27, 15 July 2024 (UTC)[reply]

This is great. Thank you. I've always wondered how we deal with retracted articles and now you've presented at least some alerting automation. --User:Ceyockey (talk to me) 03:48, 16 July 2024 (UTC)[reply]