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'''Tubulin, epsilon 1''' is a [[protein]] in humans that is encoded by the TUBE1 [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: Tubulin, epsilon 1 | url = |
'''Tubulin, epsilon 1''' is a [[protein]] in humans that is encoded by the TUBE1 [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: Tubulin, epsilon 1 | url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=51175}}</ref> |
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This gene encodes a member of the [[tubulin]] superfamily. This protein localizes to the [[centriole|centriolar]] sub-distal appendages that are associated with the older of the two centrioles after [[centrosome]] duplication. This protein plays a central role in organization of the [[microtubule]]s during centriole duplication |
This gene encodes a member of the [[tubulin]] superfamily. This protein localizes to the [[centriole|centriolar]] sub-distal appendages that are associated with the older of the two centrioles after [[centrosome]] duplication. This protein plays a central role in organization of the [[microtubule]]s during centriole duplication |
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Revision as of 18:37, 31 October 2017
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| Aliases | TUBE1, TUBE, dJ142L7.2, tubulin epsilon 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 607345; MGI: 1919174; HomoloGene: 17762; GeneCards: TUBE1; OMA:TUBE1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene.[5] This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000074935 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019845 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Tubulin, epsilon 1".
Further reading
- Chang P, Giddings TH, Winey M, Stearns T (January 2003). "Epsilon-tubulin is required for centriole duplication and microtubule organization". Nature Cell Biology. 5 (1): 71–6. doi:10.1038/ncb900. PMID 12510196.
- Zanic M, Stear JH, Hyman AA, Howard J (October 2009). May RC (ed.). "EB1 recognizes the nucleotide state of tubulin in the microtubule lattice". PLoS One. 4 (10): e7585. doi:10.1371/journal.pone.0007585. PMC 2761489. PMID 19851462.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Chang P, Stearns T (January 2000). "Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology. 2 (1): 30–5. doi:10.1038/71350. PMID 10620804.
