Effects of the storage conditions on the stability of natural and synthetic cannabis in biological matrices for forensic toxicology analysis: An update from the literature

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Didesmethylcitalopram
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Pharmacokinetic data
Elimination half-life100 h
Identifiers
  • (RS or S)-1-[3-aminopropyl]-1-
    (4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H17FN2O
Molar mass296.345 g·mol−1
3D model (JSmol)
  • c1cc(ccc1[C@]2(c3ccc(cc3CO2)C#N)CCCN)F
  • InChI=1S/C18H17FN2O/c19-16-5-3-15(4-6-16)18(8-1-9-20)17-7-2-13(11-21)10-14(17)12-22-18/h2-7,10H,1,8-9,12,20H2/t18-/m0/s1 ☒N
  • Key:RKUKMUWCRLRPEJ-SFHVURJKSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Didesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic).[1] Didesmethylescitalopram is an active metabolite of the antidepressant escitalopram, the S-enantiomer of citalopram. Like citalopram and escitalopram, didesmethyl(es)citalopram functions as a selective serotonin reuptake inhibitor (SSRI), and is responsible for some of its parents' therapeutic benefits.

See also

References

  1. ^ Rop PP, Durand A, Viala A, Jørgensen A (April 1990). "Simultaneous determination of citalopram, monodesmethylcitalopram and didesmethylcitalopram in plasma by high-performance liquid chromatography after column extraction". Journal of Chromatography. 527 (1): 226–32. doi:10.1016/s0378-4347(00)82105-2. PMID 2365786.