Potency and safety analysis of hemp-derived delta-9 products: The hemp vs. cannabis demarcation problem

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Clinical data
Other namesAMB-CHMICA
Legal status
Legal status
  • Methyl N-{[1-(cyclohexylmethyl)-1H-indol-3-yl]carbonyl}-L-valinate
CAS Number
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass370.493 g·mol−1
3D model (JSmol)
  • CC(C)[C@@H](C(=O)OC)NC(=O)c1cn(c2c1cccc2)CC3CCCCC3
  • InChI=1S/C22H30N2O3/c1-15(2)20(22(26)27-3)23-21(25)18-14-24(13-16-9-5-4-6-10-16)19-12-8-7-11-17(18)19/h7-8,11-12,14-16,20H,4-6,9-10,13H2,1-3H3,(H,23,25)/t20-/m0/s1

MMB-CHMICA (AMB-CHMICA) is a designer drug and synthetic cannabinoid.[1][2][3] In 2018, it was the sixth-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.[4]


  1. ^ Göl E, Çok I (January 2019). "New psychoactive substances in Turkey: Narcotics cases assessed by the Council of Forensic Medicine between 2016 and 2017 in Ankara, Turkey". Forensic Science International. 294: 113–123. doi:10.1016/j.forsciint.2018.11.003. PMID 30502695. S2CID 56176934.
  2. ^ Mardal M, Dalsgaard PW, Qi B, Mollerup CB, Annaert P, Linnet K (April 2018). "Metabolism of the synthetic cannabinoids AMB-CHMICA and 5C-AKB48 in pooled human hepatocytes and rat hepatocytes analyzed by UHPLC-(IMS)-HR-MSE". Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1083: 189–197. doi:10.1016/j.jchromb.2018.03.016. PMID 29549742.
  3. ^ Wagmann L, Stiller RG, Fischmann S, Westphal F, Meyer MR (October 2022). "Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterases". Archives of Toxicology. 96 (10): 2755–2766. doi:10.1007/s00204-022-03332-z. PMC 9352624. PMID 35788413. S2CID 250281976.
  4. ^ "Emerging Threat Report: Annual 2018" (PDF). Special Testing and Research Laboratory, Drug Enforcement Administration.