January 7, 2020
Laboratory Informatics Weekly Update

Volume 18, Issue 1


In This Issue

 Upcoming Webinars

01/22/2020 - Computer System Validation – The Big Picture

01/28/2020 - Astrix Webinar – Supporting Your Laboratory Informatics Ecosystem with Laboratory Informatics as a Service (LIaaS)

 Journal Articles

ChromaWizard: An open-source image analysis software for multicolor fluorescence in situ hybridization analysis

In this brief article published in Cytometry Part A, researchers at the Austrian Centre for Industrial Biotechnology present their open-source multiplex fluorescence in situ hybridization (M‐FISH) software for chromosome painting. The tool—ChromaWizard—acts as a free and open-source option for hybridization analysis, integrating "image processing, multicolor integration, chromosome separation, and visualization with false color assignments." The software can handle images in TIFF, PNG, and JPEG formats and provides robust visualization tools. The authors conclude that ChromaWizard "allows direct inspection of the original hybridization signals and enables either manual or automatic assignment of colors, making it a functional and versatile tool that can also be used for other multicolor applications."

CytoConverter: A web-based tool to convert karyotypes to genomic coordinates

In this brief article published in BMC Bioinformatics, Wang and LaFramboise address the topic of cytogenetic data and their genomic coordinates, which the authors describe as "precisely [specifying] a chromosomal location according to its distance from the end of the chromosome." The authors note that despite changes in techniques over the years, the use of karyotype and cytogenetic nomenclature was the primary way of characterizing aberrations in chromosomes, and those methods are still being used today. Additionally, archival data used karyotypes and cytogenetic nomenclature. Given the lack of a maintained, robust tool for converting that nomenclature to genomic coordinates, the authors address their creation, CytoConverter, and explain how it accomplishes such conversions. They conclude that the tool should have "considerable value to the community for analyzing archival patient samples, as well as samples for which higher-resolution copy number data is unavailable."
 Featured Jobs

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Laboratory Technology Management & Planning

This document is based on a presentation delivered by chemist and automation consultant Joe Liscouski at the 2nd Annual Lab Asset & Facility Management in Pharma 2019 conference held in San Diego, CA, on October 22nd, 2019. It is not a verbatim transcript, but an expansion of the material presented. The presentation addressed the importance of effective technology management and planning within scientific work. With improved technology management and planning, "[t]hat work should yield better organized systems, reduced costs, better workflows, and improved ROI. How do you go about it? That is what we’ll start to address in this material."
 Featured Discussions

12/17/2019 - strategic partners for new LIMS app platform.

12/10/2019 - I am an instrument vendor and I have a question regarding data standard

12/10/2019 - Thoughts on hiring scientific freelancers

12/05/2019 - Mindray BC3600 and LIS connection problem

11/13/2019 - ELN Usage


Benefits you should bank on by using a LIMS

Laboratory Relocation Best Practices

LIMS Master Data Best Practices Part 3: Maintenance and Scalability

Disaster Recovery Plans for Your LIMS or ELN


01/07/2020 - Enhanced QC Functionality for Matrix Gemini LIMS

01/07/2020 - Further Improving Efficiency in Laboratory Testing

01/07/2020 - Enhanced Chromatography Data System Software Delivers Improved Efficiency and Compatibility Across the Latest Generation of Analytical Instruments

01/07/2020 - CompuGroup Medical Streamlines its Laboratory Software

 Upcoming Trade Events

01/23/2020 - International Conference on Health and Medical Informatics Systems 2020

01/25/2020 - SLAS2020

02/17/2020 - SmartLab Exchange Europe

 Bid Opportunities

01/20/2020 - Presolicitation: Chemical and Geotechnical Analyses of Environmental Samples

02/17/2020 - Request for Bids: Laboratory Information Management System for Washington State University College of Veterinary Medicine

Become a Sponsor
CSols Inc.
Autoscribe / Autoscribe Informatics, Inc.
Thermo Fisher Scientific
LabLynx, Inc.
Abbott Informatics Corporation
Astrix Technology Group
Blaze Systems Corporation
ApolloLims / Common Cents Systems, Inc.
Computing Solutions, Inc.
OnQ Software
Paperless Lab Academy
Hudson Robotics, Inc.

E-mail your feedback or questions to us at: newsletter@limsforum.com

Mail us: LabLynx, Inc. P.O. Box 673966 Marietta, GA 30006

Telephone: 866-LabLynx (522-5969)