Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7gene.[5][6]
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.[6]
Holder N, Klein R (1999). "Eph receptors and ephrins: effectors of morphogenesis". Development. 126 (10): 2033–44. doi:10.1242/dev.126.10.2033. PMID10207129.
Wilkinson DG (2000). "Eph receptors and ephrins: regulators of guidance and assembly". Int. Rev. Cytol. International Review of Cytology. 196: 177–244. doi:10.1016/S0074-7696(00)96005-4. ISBN 978-0-12-364600-2. PMID10730216.
Fox GM, Holst PL, Chute HT, et al. (1995). "cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases". Oncogene. 10 (5): 897–905. PMID7898931.
Ciossek T, Ullrich A (1997). "Identification of Elf-1 and B61 as high affinity ligands for the receptor tyrosine kinase MDK1". Oncogene. 14 (1): 35–43. doi:10.1038/sj.onc.1200800. PMID9010230. S2CID24727040.
Stubbs J, Palmer A, Vidovic M, Marotte LR (2000). "Graded expression of EphA3 in the retina and ephrin-A2 in the superior colliculus during initial development of coarse topography in the wallaby retinocollicular projection". Eur. J. Neurosci. 12 (10): 3626–36. doi:10.1046/j.1460-9568.2000.00251.x. PMID11029633. S2CID37988439.